Autism and attention deficit hyperactivity disorder (ADHD) are neurodevelopmental conditions that profoundly influence the way we are in the world, in childhood but continues to do so in adulthood. In our current urban world, characterized by high speed, deadlines, full agendas, multitasking, (social) performance pressure, and a bombardment of stimuli, all of us but people with autism and ADHD even more so may experience sensory overload, attention problems, and too much stress. Those who live with people with autism or ADHD, whether they are partners, parents, or children, may also experience high levels of stress, because they feel or take over their stress. Mindfulness can help here to regulate sensory overload, attention, and intrapersonal and interpersonal stress. Whether you’re a mindfulness practitioner, therapist, educator, or living with (a person with) autism or ADHD, this talk will provide deeper understanding and practical tools to regulate the stress that comes with autism and ADHD.